Platelet count decrease in dengue is due to the destruction of platelets by the dengue virus. Dengue is a viral infection caused by the dengue virus, which is transmitted to humans by the Aedes mosquito.
When a person is infected with the dengue virus, the virus replicates within the host's cells, including the cells that make platelets. As the virus replicates, it destroys these cells, leading to a decrease in the number of platelets in the blood, a condition known as thrombocytopenia.
The destruction of platelets can occur in two ways:
Direct destruction: The virus can directly infect and destroy the platelets, leading to a decrease in the number of platelets in the blood.
Indirect destruction: The virus can also induce an immune response that targets and destroys platelets. This happens when the body's immune system recognizes the platelets as foreign and attacks them, leading to a decrease in the number of platelets in the blood.
The severity of thrombocytopenia in dengue can vary, with some patients experiencing only mild thrombocytopenia, while others may experience a severe decrease in platelet count which can lead to bleeding. Severe dengue can also cause other complications such as organ failure and shock.
In summary, platelet count decrease in dengue is caused by the destruction of platelets by the dengue virus, which can occur through direct destruction or an immune response that targets and destroys platelets. The severity of thrombocytopenia can vary and can lead to other complications such as bleeding and organ failure.
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